Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_197174eb93dc97e67c46af4d62c1e9e7 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-52 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-249 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-248 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-468 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-36 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
filingDate |
2016-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2022-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd2ec6301d6b97fbb1bcfd95181b8166 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4512f122b958b7459242b1e5d813268b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7dd99bbc7a2eaf9d5781878eb4187b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a07aed9780ea31f6a2a1f3158efb097f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_615fef51f326dba19e39602e5977a998 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16d0cbaaf23c17056721510c33954d96 |
publicationDate |
2022-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
AU-2016232349-B2 |
titleOfInvention |
Methods of purifying bispecific antibodies |
abstract |
The invention relates to the purification of bispecific antibodies carrying a different specificity for each binding site of the immunoglobulin molecule from a mixture of monospecific antibodies. The bispecific antibodies are composed of a single heavy chain and two different light chains, one containing a Kappa constant domain and the other a Lambda constant domain. This invention in particular relates to the isolation of these bispecific antibodies from mixtures that contain monospecific antibodies having two Kappa light chains or portions thereof and monospecific antibodies having two Lambda light chains or portions thereof. The invention also provides the methods of efficiently purifying these bispecific antibodies. |
priorityDate |
2015-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |