| abstract |
Embodiments herein report compositions of and methods for making and using alpha-1 antitrypsin (AAT) fusion molecules or peptide derivatives thereof. In certain embodiments, compositions and methods relate to generating an AAT fusion molecule of use in pharmaceutically acceptable compositions to treat a subject in need of AAT therapy or treatment. In other embodiments, compositions and methods disclosed herein concern linking AAT or derivative thereof to an immune fragment. Fig. 7A Joint Scores following MSU-C16 Gouty Arthritis 1.256 p=0.032 l. j -, 0.25 - -r-- -r 'IV ,? <:,Q |