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filingDate 2016-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4eeea63e4df380bc68a6a30d36cb40fc
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publicationDate 2019-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber AU-2016214439-B2
titleOfInvention Use of HLA-B27 homodimers for cancer treatment
abstract The invention relates to a HLA-B27 Fc homodimer or a HLA-B27 Fc fusion protein homodimer for use in the treatment or prevention of cancer. The Fc homodimer comprises or consists of a first and a second monomer, and each monomer comprises a HLA-B27 chain. The Fc fusion protein homodimer further comprises a protein stabilizing polypeptide sequence and optionally an amino acid linker. Further aspects of the invention provide combination medicaments comprising the HLA-B27 Fc homodimer and immune checkpoint inhibitors.
priorityDate 2015-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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