Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_60da379fb33c192ef77f86a60c5ac029 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e071d18fea054bf8d1420d483e78ed1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb9c6b40161bafe7bd55f0b4defcea04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-20 |
filingDate |
2016-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a069ee0f7afc5b0f6acce946e39f42a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30e989b0e2abee644a117a82eb459511 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ea2403c09630ff8b14d02ad39b5f0e9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_873bd655472614733dd290469d0a67e3 |
publicationDate |
2016-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
AU-2016204339-A1 |
titleOfInvention |
Compositions and methods for the treatment of infections and tumors |
abstract |
PD-I antagonists are disclosed that can be used to reduce the expression or activity of PD-1 in a subject. An immune response specific to an infectious agent or to tumor 5 cells can be enhanced using these PD- I antagonists in conjunction with an antigen from the infectious agent or tumor. Thus, subjects with infections, such as persistent infections can be treated using PD-I antagonists. In addition, subjects with tumors can be treated using the PD-1 antagonists. In several examples, subjects can be treated by transplanting a therapeutically effective amount of activated T cells that 10 recognize an antigen of interest and by administering a therapeutically effective amount of a PD-I antagonist. |
priorityDate |
2006-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |