abstract |
Abstract [Abstract] [Problem] 5 The present invention provides a compound which is useful as an active ingredient of a pharmaceutical composition, in particular, a pharmaceutical composition for preventing and/or treating VAP-1-related diseases. [Means for Solution] The present inventors have conducted intensive studies on a compound having a 10 VAP-1 inhibitory activity, and as a result, they have found that the compound or a salt thereof of the present invention exhibits an excellent VAP-I inhibitory activity and is useful for preventing and/or treating.VAP- 1-related diseases, in particular, diabetic nephropathy or diabetic macular edema, thereby completing the present invention. In addition, the present invention relates to a pharmaceutical composition, in particular, a 15 pharmaceutical composition for preventing and/or treating VAP- -related diseases, which comprises the compound or a salt thereof of the present invention, and an excipient. [Selected Figure] Nil |