http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2016102274-A4
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a38335d7eddda25a301388f254a7ad2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-22 |
| filingDate | 2016-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40ee3145034012c6508cc45dca4af410 |
| publicationDate | 2017-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AU-2016102274-A4 |
| titleOfInvention | Naftifine drug intermediates N- methyl-1-naphthalene methylamine synthesis method |
| abstract | Naftifine drug intermediates N- methyl-i -naphthalene methylamine synthesis method, comprising the following steps: equipped with a stirrer, a thermometer, a condenser and a dropping funnel, the reaction vessel was added 130ml propionitrile solution, 210ml methyl amine (3), reducing the solution temperature to 13-16 C, controlling the stirring speed 110-130rpm, 0.31mol amine methyl naphthalene(2) was added slowly, controlled dropping time in 3-4h, elevated the solution temperature to 40-45 C, standing for 30-36h, evaporated propionitrile , the residue was added 230ml cyclohexane solution, successively washed with potassium bisulfite solution, washed with salt solution, dehydrated with dehydration agent, vacuum distillation, collecting fractions of 110--115 C, recrystallized from nitromethane solution, got N methyl-1 -naphthalene methanamine crystals . |
| priorityDate | 2015-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.