| abstract |
Methods of reducing chemical degradant formation, such as those resulting from dimer formation in disulfide bridge-closed ring-bearing polypeptides, such as oxytocin, in a solid-state; to heat stable pharmaceutical compositions having improved physio- or chemical stability, to inhalers and dosage forms of such compositions, to methods of production of and treatment of diseases and or conditions, such as post partum hemhorrage, with such compositions. |