http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2015215938-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e3830f35387a1c32061dea3ee310851 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02 |
| filingDate | 2015-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9dd5215d025303b37cace11f4e34ce6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a83f51a6433a8fedd54305b07ca1f710 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eecda947870561112c8fd83d0d61de14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa838e3cc60525caa9f9c0ece4c5b367 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29fcdbc9951c14119f62b99100f60905 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6c6248b4bfa71a6becdd717332a82d5 |
| publicationDate | 2018-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AU-2015215938-B2 |
| titleOfInvention | RNA preparations comprising purified modified RNA for reprogramming cells |
| abstract | RNA PREPARATIONS COMPRISING PURIFIED MODIFIED RNA FOR REPROGRAMMING CELLS The present invention provides compositions and methods for reprogramming somatic cells using purified RNA preparations comprising single-strand mRNA encoding an iPS cell induction factor. The purified RNA preparations are preferably substantially free of RNA contaminant molecules that: i) would activate an immune response in the somatic cells, ii) would decrease expression of the single-stranded mRNA in the somatic cells, and/or iii) active RNA sensors in the somatic cells. In certain embodiments, the purified RNA preparations are substantially free of partial mRNAs, double-stranded RNAs, un-capped RNA molecules, and/or single-stranded run on mRNAs. |
| priorityDate | 2009-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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