http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2015201794-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24e5038820410b1229df1ddfb6700298 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate | 2015-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc9c5032fe2e0d219276d640cf8e7edd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f353ae95f41284a741fa62f3cf0bfa44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd04ee3704336ed4d674c9b47643605d |
| publicationDate | 2015-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AU-2015201794-A1 |
| titleOfInvention | STABLE AND SOLUBLE ANTIBODIES INHIBITING TNFa |
| abstract | The present invention relates to particularly stable and soluble scFv antibodies and Fab fragments specific for TNF, which comprise specific light chain and heavy chian sequences that are optimized for stability, solubility, in vitro and in vivo binding of TNF, and low immunogenicity. Said antibodies are designed for the diagnosis and/or treatment of TNF mediated disorders. The nucleic acids, vectors and host cells for expression of the recombinant antibodies of the invention, methods for isolating them and the use of said antibodies in medicine are also disclosed. |
| priorityDate | 2008-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1022.