Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e071d18fea054bf8d1420d483e78ed1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-5027 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M23-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M21-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M41-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0062 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02 |
filingDate |
2014-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15b334a9e83cb7015633de85814a40b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_494adefb84aa1a89333591470f34f934 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d57c56d6b4de18039b4d70b378ab0210 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e3f5bb8f13fac64b0fc0e28f0ac19e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5836631ec7b230af844d66705eaeee6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb68a8d03523423b29ac40671d7f78e0 |
publicationDate |
2016-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
AU-2014386209-A2 |
titleOfInvention |
Low shear microfluidic devices and methods of use and manufacturing thereof |
abstract |
Provided herein relates to systems and methods for producing and using a body having a central channel separated by one or more membranes. The membrane(s) are configured to divide the central channel into at least one mesochannel and at least one microchannel. The height of the mesochannel is substantially greater than the height of the microchannel. A gaseous fluid can be applied through the mesochannel while a liquid fluid flowing through the microchannel. The systems and methods described herein can be used for various applications, including, e.g., growth and differentiation of primary cells such as human lung cells, as well as any other cells requiring low shear and/also stratified structures, or simulation of a microenvironment in living tissues and/or organs (to model physiology or disease states, and/or to identify therapeutic agents and/or vaccines). The systems and methods can also permit co-culture with one or more different cell types. |
priorityDate |
2013-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |