http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2014204569-B9
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a43ef275ae6f6fafc66975041eb60aa7 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-24 |
| filingDate | 2014-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e06985817733436b8ae1f4271cfd2f13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b33b69ff204eb2497fa3058e378cc5e9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e64664b34e94348269a92f9b502f3bad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a444b661bc6a547094af5b596c5463a |
| publicationDate | 2017-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AU-2014204569-B9 |
| titleOfInvention | High mannose proteins and methods of making high mannose proteins |
| abstract | P:\OPER\WM\TMrns" lk Theraplestfi(0227Dv Claim.dacIO(St/2007 The invention features a method of producing a high mannose glucocerebrosidase (hmGCB) which includes: providing a cell which is capable of expressing glucocerebrosidase (GCB), and allowing production, of GCB having a precursor oligosaccharide under conditions which prevent the removal of at least one mannose residue distal to the pentasaccharide core of the precursor oligosaccharide of GCB, to thereby produce an hmGCB preparation. Preferably, the condition which prevents the removal of at least one mannose residue distal to the pentasaccharide core is inhibition of a class I processing manosidase and/or a class 2 processing manosidase. The invention also features an hmGCB preparation and methods of using an hmGCB preparation. |
| priorityDate | 2000-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 194.