http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2014202415-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7fe23d6754a4999c6cbe01c3dd82b445 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H23-00 |
| filingDate | 2014-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1451542ecfd7508989aadc7fbf8a15d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1220270c783ad76be053b2ae20ca72f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e18bfd4deef66cd9cdcc1458617feb2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c62d90e1151e4c05952355aad144348 |
| publicationDate | 2014-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AU-2014202415-A1 |
| titleOfInvention | Cyanocobalamin low viscosity aqueous formulations for intranasal delivery |
| abstract | A stable pharmaceutical aqueous solution of cyanocobalamin comprised of cyanocobalamin and water wherein said solution of cyanocobalamin is suitable for intranasal administration, has a viscosity of less than about 1000 cPs, and yields a bioavailability of cyanocobalamin when administered intranasally of at least about 5% relative to an intramuscular injection of cyanocobalamin. The present invention is also directed towards a method for elevating the vitamin B 12 levels in the cerebral spinal fluid (CSF) comprising administering intranasally a sufficient amount of a cyanocobalamin solution so as to increase the average ratio of vitamin B12 in the CSF to that in the blood serum (B12 CSF/B12 Serum x 100) to at least about 1.1 comprising intranasally administering an aqueous solution of a cyanocobalamin, wherein said solution of cyanocobalamin has a bioavailability of at least 5% relative to an intramuscular injection of a cyanocobalamin. |
| priorityDate | 2006-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.