http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2013328352-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c06bc0c2d1b16f9d16470b7e30874649 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06026 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-42 |
| filingDate | 2013-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05086e677f34ef94b054ffdc360a728d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8608988b33cd31d47d4a692378f1f4f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c7235ab6c344274a50671ea3230d48c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f61ab13a392a04dd165213a4abc7421 |
| publicationDate | 2015-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AU-2013328352-A1 |
| titleOfInvention | An improved process for preparation of Perindopril intermediate |
| abstract | The present invention relates to an improved process for the preparation of (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-lH-indole-2-carboxylic acid benzyl ester( the compound of formula II) comprising reacting (2S,3aS,7aS)-octahydro-1H-indole-2-carboxylic acid phenylmethyl ester 4-methylbenzenesulfonate (the compound of formula III) with N-[(S)-ethoxycarbonyl-1-butyl]-(S)-alanine (the compound of formula IV), using 1-hydroxybenzotriazole (HOBT), dicyclohexylcarbodiimide (DCC) and triethylamine in the presence of toluene as a solvent at a temperature of 5°C to 40°C. |
| priorityDate | 2012-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 116.