Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_46cb3dfdd38a34ce27bf0e2323d90a6a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fbb16b39443f72f271c474607c90fced |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02E50-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y402-03047 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y503-03002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y205-01 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P5-007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 |
filingDate |
2013-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2019-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a59ea2a93bf4df5432dc4b0b4689f50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c6cc1e0850129c8c74664073f6da2c6 |
publicationDate |
2019-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
AU-2013299608-B2 |
titleOfInvention |
Methods for stabilizing production of acetyl-coenzyme a derived compounds |
abstract |
The present disclosure relates to the use of a switch for the production of heterologous non-catabolic compounds in microbial host cells. In one aspect, provided herein are genetically modified microorganisms that produce non-catabolic compounds more stably when serially cultured under aerobic conditions followed by microaerobic conditions, and methods of producing non-catabolic compounds by culturing the genetically modified microbes under such culture conditions. In another aspect, provided herein are genetically modified microorganisms that produce non-catabolic compounds more stably when serially cultured in the presence of maltose followed by the reduction or absence of maltose, and methods of producing non-catabolic compounds by culturing the genetically modified microbes under such culture conditions. |
priorityDate |
2012-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |