http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2013263788-A1

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filingDate 2013-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97bf7eec8cc2e127f98d9487af3df3c2
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publicationDate 2013-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber AU-2013263788-A1
titleOfInvention Development of dengue virus vaccine components
abstract H:\fm\Intrwovn\NRPortbl\DCC\FMT\5853394_I.doc-28/1/2013 The invention is related to a dengue virus or chimeric dengue virus that contains a mutation in the 3' untranslated region (3'-UTR) comprising a A30 mutation that removes the TL-2 homologous structure in each of the dengue virus serotypes 1, 2, 3, and 4, and nucleotides additional to the A30 mutation deleted from the 3'-UTR that removes sequence in the 5' direction as far as the 5' boundary of the TL-3 homologous structure in each of the dengue virus serotypes 1, 2, 3, and 4, or a replacement of the 3'-UTR of a dengue virus of a first serotype with the 3'-UTR of a dengue virus of a second serotype, optionally containing the A30 mutation and nucleotides additional to the A30 mutation deleted from the 3'-UTR; and immunogenic compositions, methods of inducing an immune response, and methods of producing a dengue virus or chimeric dengue virus.
priorityDate 2006-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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