http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2013234422-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c89ce4d9ac03f9acd8ddede1162f94d |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D285-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-14 |
| filingDate | 2013-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7b7aaf9795d9eeee9ae5a96c9db65b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1950059b0e285ae2d786fc594425402e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1151cd9fdae4b24360fa06cae9fed44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48b6fa5a503152e47d9d707cda3d0e5f |
| publicationDate | 2014-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AU-2013234422-B2 |
| titleOfInvention | Iminothiadiazine dioxide compounds as BACE inhibitors, compositions, and their use |
| abstract | IMINOTHIADIAZINE DIOXIDE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE Abstract In its many embodiments, the present invention provides certain iminothiadiazine dioxide compounds, including compounds Formula (I) and include stereoisomers thereof, and pharmaceutically acceptable salts of said compounds stereoisomers, wherein each of R', R 2, R', R4, R 5, R9, ring A, ring B3, mn, n, p, -L1-,L2-, and L-3 is selected independently and as defined herein. The novel iminothiadiazine dioxide compounds of the invention have surprisingly been found to exhibit properties which are expected to render them advantageous as BACE inhibitors and/or for the treatment and prevention of various pathologies related to $-amyloid (A$) production. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use in treating pathologies associated with amyloid beta (A$) protein, including Alzheimers disease, are also disclosed. |
| priorityDate | 2009-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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