http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2013203924-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_60da379fb33c192ef77f86a60c5ac029 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_add969a0675fe4f65a6bddf775b16068 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4965 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-497 |
| filingDate | 2013-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d4413ef5eedced82b73e8e1aed8a4d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ec0b665272b86dbf8ca21890a60c045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fae404bbeb463890cc4c2f078745bfc5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91e075c1f3ec780235a542aee2d436b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa6bfe035347a597e3dae2a94be1a21a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a9a2c5fcb1936246982ac4e7feaea02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33b1793a73531d68026035ce28944cc7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5bcc2e1d35849eedbd61d630f18454b |
| publicationDate | 2013-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AU-2013203924-A1 |
| titleOfInvention | NMDA receptor antagonists for neuroprotection |
| abstract | Provided are compounds, pharmaceutical compositions and methods of treatment or prophylaxis of disorders associated with NMDA receptor activity, including neuropathic pain, stroke, traumatic brain injury, epilepsy, and related neurologic events or neurodegeneration. Compounds are of the general Formula I, or a pharmaceutically acceptable salt, ester, prodrug or derivative thereof are provided: Formula I wherein: each (L)k-Arl is a substituted or unsubstituted, mono or bicyclic aryl or heteroaryl; W is a bond, alkyl, or alkenyl; X is a bond, NR 1 or 0 and each R 1 and R2 is independently H, alkyl, alkenyl or aralkyl or R 1 and R2 taken together form a 5-8 membered ring; R3 R 6 are selected from certain specific substituents or a carbonyl; Y is a bond, 0, S, SO, SO 2 , CH2, NH, N(alkyl), or NHC(=O); and Z is OH, NR6R7 , NR 8SO2(alkyl), NR8C(O)NR 6R 7, NR8C(O)O(alkyl), NR 8- dihydrothiazole, or NR 8-dihydroimidazole or wherein Z can fuse with Ar2 to form selected heterocycles. |
| priorityDate | 2007-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 455.