http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2013203374-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d229687f0e02f1a09038e165f28be97f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2013-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbac2a1475027198d43c78194d7d91b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_420393d5bf8ee4a27b9a540437a161fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a572336a00e655750177b8dd05710683 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ce76688a26ef56ee4cbb1609283dca6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4674c2447a4624079b2d9707c69a1f6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a396a3bf23cdd91bd724bfb13757bc64 |
| publicationDate | 2013-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AU-2013203374-A1 |
| titleOfInvention | Method for generating aptamers with improved off-rates |
| abstract | [00261] The present disclosure describes improved SELEX methods for producing aptaners that are capable of binding to target molecules and improved photoSELEX methods for producing photoreactive aptamers that are capable of both binding and covalently crosslinking to target molecules. Specifically, the present disclosure describes methods for producing aptamers and photoapianers having slower dissociation rate constants than are obtained using prior SELEX and photoSELEX methods. The disclosure further describes apiamers'and photoaptamers having slower dissociation rate constants than those obtained using prior methods. In addition, the disclosure describes aptamer constructs that include a variety of functionalities, including a cleavable element, a detection element and a capture or immobilization element. |
| priorityDate | 2007-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 384.