http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2013201606-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aca152ba4602da5909c80dcbdef46ef5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ed7919c5019f9a037e4036b8ee0dbe10 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 |
filingDate | 2013-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be5fdfe53f6b39fb3736dd71c150a62c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c1cb1282cc2b7d3c8e68b7a94425436 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bce4ea6ded491b7579f7e4fbdf408abf |
publicationDate | 2016-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | AU-2013201606-B2 |
titleOfInvention | Methods for treating conditions associated with MASP-2 dependent complement activation |
abstract | In one aspect, the invention provides methods of inhibiting the effects of MASP-2 dependent complement activation in a living subject. The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to Inhibit MASP-2-dependent complement activation. In some embodiments, the MASP-2 inhibitory agent inhibits cellular injury associated with MASP-2-mediated alternative complement pathway activation, while leaving the classical (Clq -dependent) pathway component of the immune system Intact. In another aspect, the invention provides compositions for inhibiting the effects of lectin dependent complement activation, comprising a therapeutically effective amount of a MASP-2 inhibitory agent and a pharmaceutically acceptable carrier. |
priorityDate | 2011-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1066.