| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9a95d0c63b9b3f2bc8e8d6b45fbe7789 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-71
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate |
2013-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76a4ee6483a6e1b003f2b037cb89ef3e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8a368a7b5546044c18860d695b7cf71
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2425e614dd459dd79a4941f8cf14eddd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34970b4c5981bc18a83c6d6e5d2d9d72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cc0d79a3181f7d8af496802c035ea6b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be070cd02c591fe3684b56cd2610c9e1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b40583ec4274aa4e0152768a576c3dc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ebc7bd0cea594404b6f7fabd1792620e |
| publicationDate |
2013-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
AU-2013200209-A1 |
| titleOfInvention |
Recombinant anti-epidermal growth factor receptor antibody compositions |
| abstract |
Recombinant anti-epidermal growth factor receptor antibody compositions The invention relates to the field of recombinant antibodies for use in human cancer therapy. More specifically the invention provides compositions or mixtures of antibodies capable of binding human EGFR. Antibody compositions with 3 or more antibodies have shown synergy in reduction of proliferation of representative cancer cell lines. Advantageous results have also been obtained with a composition comprising two different chimeric anti-hEGFR antibodies which show a new mechanism of action based on rapid and efficient receptor internalisation, induction of terminal differentiation and subsequent tumour eradication in an animal model. The antibodies of the invention can be manufactured in one bioreactor as a polyclonal antibody. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11124575-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3585814-A4 |
| priorityDate |
2007-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |