| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9f647989e1b9ffcd4d9ab219792a5dbf |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B23D45-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B27B9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B23Q13-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F220-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B27B5-29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B25F5-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-785
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 |
| filingDate |
2012-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c9d3020f6b490bf395400e3593b4523
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7ade95b3a1468043a84ef8fa284b878
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59103db1e4346743b0f6b6089174ad3f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67e68403d86823f177d4c7e36acc82a0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3d880733ece274215d657f894297e10 |
| publicationDate |
2014-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
AU-2012377385-A2 |
| titleOfInvention |
Poly(acrylate) polymers for in vivo nucleic acid delivery |
| abstract |
The present invention is directed membrane active poly(acrylate) polymers and compositions for targeted delivery of RNA interference (RNAi) polynucleotides cells in vivo. RNAi polynucleotides are conjugated to the poly(acrylate) polymers and the polymers are reversibly modified to enable in vivo targeted delivery. Membrane activity of the poly(acrylate) provides for movement of the RNAi polynucleotides from outside the cell to inside the cell. Reversible modification provides physiological responsiveness. |
| priorityDate |
2012-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |