Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b09f893b262cefd50c5e76c4b85d1c0a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02E50-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y102-01012 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-815 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-635 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y102-01012 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0008 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-395 |
filingDate |
2012-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_134cd422d568b158c70bf636a0df15a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b32c1fdc5d452f8b6d4175e437a97f45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7349030ce292013ea0de97289629297 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_365bd743a7ed3c660d5a0ead6485bceb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd749b65c68387adc62821557ca05fa4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c139aed918dbe6b5c2109f0975966e1c |
publicationDate |
2014-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
AU-2012320421-A1 |
titleOfInvention |
Regulatable promoter |
abstract |
A method of producing a protein of interest (POI) by culturing a recombinant eukaryotic cell line comprising an expression construct comprising a regulatable promoter and a nucleic acid molecule encoding a POI under the transcriptional control of said promoter, comprising the steps a) cultivating the cell line with a basal carbon source repressing the promoter, b) cultivating the cell line with a limited amount of a supplemental carbon source de-repressing the promoter to induce production of the POI at a transcription rate of at least 15% as compared to the native pGAP promoter, and c) producing and recovering the POI; and further an isolated regulatable promoter and a respective expression system. |
priorityDate |
2011-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |