| abstract |
The present invention provides antibodies that bind to Tie2 and methods of using same. According to certain embodiments of the invention, the antibodies are fully human antibodies that bind to human Tie2 and block the interaction between Tie2 and one or more Tie2 ligands such as angtopotetin 1 (Ang1), angtopoietin 2 (Ang2), angiopoietin 3 (Ang3) and/or angtopoietin 4 (Ang4). The antibodies of the invention are useful, |