| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6ff383e837bc02f8d53d5f307815d0c3 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6855
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6809
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6811
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6813
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6834
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6862 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2012-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2017-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6921161e750e2b0ca2e377409b80fb40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa1bbb5f723e970a36a4fbb34ed02477
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c4fb0b1a4ded2e760fbceb4686507d1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e4a67a57d0a9723a73c83517c64440e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8d20a1fc55b0c4e29ec409a56c73d1e |
| publicationDate |
2017-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
AU-2012255121-B2 |
| titleOfInvention |
Methods and compositions for detecting target nucleic acids |
| abstract |
The present invention provides compositions, apparatuses and methods for detecting one or more nucleic acid targets present in a sample. Methods of the invention include utilizing two or more ligation probes that reversibly bind a target nucleic acid in close proximity to each other and possess complementary reactive ligation moieties. When such probes have bound to the target in the proper orientation, they are able to undergo a spontaneous chemical ligation reaction that yields a ligation product that is directly detected or that is amplified to produce amplicons that are then detected. The present invention also provides methods to stabilize sample RNA so that degradation does not significantly affect the results of the analysis. |
| priorityDate |
2011-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |