| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9871e02d1c09cc338f51aecbb5510178 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 |
| filingDate |
2012-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69da3460a949c82005aa1f01403c1844
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b418001b1f271217868cdc1f62ea4ee4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5980daa61dc85465e9ff4fe2f6a84620
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f6e866fb8885de4c638d1f5cda95ddb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7dfd2971a033674eb1bea2548b7476aa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ac684f0116582fb83a65b70075a6d72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a72007460dee73ba057b03278d405ad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca0b37fe6f2f2e083699b0e43faeecfe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7768aed80d8803613c12a7fb42d54a7d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0249bb7bb3ad75cf0ee68bd4ec084c24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3bce4bfae35001b1ece730858d07436
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_571e7332c93cfb2349fd28af50053a87 |
| publicationDate |
2012-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
AU-2012203432-A8 |
| titleOfInvention |
Human Monoclonal Antibodies to Activin Receptor-like Kinase-1 |
| abstract |
Abstract The present invention relates to antibodies including human antibodies and antigen-binding portions thereof that bind to the extracellular domain (ECD) of activin receptor-like kinase-1 (ALK-1) and that function to abrogate the ALK-1/TGF-beta-1/Smadl signaling pathway. The invention also relates to heavy and light chain immunoglobulins derived from human anti-ALK-1 antibodies and nucleic acid molecules encoding such immunoglobulins. The present invention also relates to methods of making human anti-ALK-1 antibodies, compositions comprising these antibodies and methods of using the antibodies and compositions. The invention also relates to transgenic animals or plants comprising nucleic acid molecules of the present invention. cJ e\J r- m >< >< 0n C" c'J C r C~j C\J C=>~ cr r -') C -- 4 Li-.J ca__J cr-Z |
| priorityDate |
2005-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |