| abstract |
Compounds of formula (1) have antibacterial activity: R2 N X- [Alk]m-Q wherein: m is 0 or 1; Q is hydrogen or cyclopropyl; Alk is an optionally substituted, divalent Cr1C6 alkylene, alkenylene or alkynylene radical which may contain an ether (-0-), thioether (-S-) or amino (-NR)- link, wherein R is hydrogen, -CN or Cr1C3 alkyl; X is -C(=0)NR-, -S(O)NR6-, -C(=0)O- or -S(=O)O- wherein R6 is hydrogen, optionally substituted Cr1C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, -Cyc, or-( C-C3 alkyl)-Cyc wherein Cyc is optionally substituted monocyclic carbocyclic or heterocyclic having 3-7 ring atoms; Z is N; R2 and R3 are as defined in the description. |