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publicationDate 2016-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber AU-2011344954-B2
titleOfInvention Peptide antibiotic over-producing strain, preparation method therefor, and use thereof
abstract Provided are an antibiotic over-producing strain, a preparation method therefor, and a use thereof. The over-producing strain is a mutant strain of Coleophoma empetri, and is deposited in China General Microbiological Culture Collection Center with a deposition number CGMCC 4129. The strain is prepared by the following steps: (a) mixing a seed solution with a deposition number FERM BP-2635 with nitrosoguanidine, to obtain a mixed solution a; (b) mixing the mixed solution a with a lyticase, to obtain a protoplast; (c) regenerating the protoplast, to obtain a single colony; and (d) culturing the single colony, to obtain the mutant strain.
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