http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2011329373-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8c54a54eaaa4d9e822a28e5293fb5c96 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6881 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6858 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2011-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81419f9321812daa768c8a16cb56a3fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2a94c409f8ec1834c08d034c7fa09f6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d62ae970eb8728f9c9c3ad4e9cb14794 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8851659327850acf3b98345ffaf8e360 |
| publicationDate | 2014-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AU-2011329373-B2 |
| titleOfInvention | Mutation detection assay |
| abstract | A method of sample analysis is provided. In certain embodiments, the method involves: a) amplifying a product from a sample that comprises both wild type copies of a genomic locus and mutant copies of the genomic locus that have a point mutation relative to said wild type copies of the genomic locus, to produce an amplified sample, where: i. the amplifying is done using a first primer and a second primer; and ii. the first primer comprises a 3' terminal nucleotide that base pairs with the point mutation and also comprises a nucleotide sequence that is fully complementary to a sequence in the locus with the exception of a single base mismatch within 6 bases of the 3' terminal nucleotide; and b) detecting the presence of said product in said amplified sample using a flap assay that employs an invasive oligonucleotide. A kit for performing the method is also provided. |
| priorityDate | 2010-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 237.