Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_927012fc47104404a2856450491513e1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-986 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-44 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6851 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-34 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-94 |
filingDate |
2011-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb0c7e26cb62043c728108dea27862a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfa2e64a74e11856bef22ffed0e17c1c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a81ab54b4ea696faffcd8043d54b71ab |
publicationDate |
2014-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
AU-2011263694-B2 |
titleOfInvention |
Mass spectrometric measurement of beta-lactamase resistances |
abstract |
The invention relates to the determination of resistances of microorganisms which produce β-lactamases, in particular "extended spectrum β-lactamases" (ESBL). The invention provides a method whereby the microbial resistance can be measured very simply and quickly by means of the catalytic effect of the microbially produced β-lactamases on β-lactam antibiotics, which consists in a hydrolytic cleavage of the β-lactam ring. The method determines the resistance of the bacteria a few hours after a suitable substrate, either a β-lactam antibiotic or a customized β-lactam derivative, has been added to a suspension of the microbes, by direct mass spectrometric measurement of the substrate breakdown caused by the β-lactamases. |
priorityDate |
2010-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |