| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec0024795f45a646ef64b3664ab8a26d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14343
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14322
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14332 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-768
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-768
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 |
| filingDate |
2011-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a00b6af64d15812fb3236604f20f911b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1dd075429bf8db8c94a548eab08dabef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47a37ffc5ca1c5df0e6cfda863e40159
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_116df06a70b76c6aac5a19bcea4b92a2 |
| publicationDate |
2012-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
AU-2011250204-A1 |
| titleOfInvention |
Modified rodent parvovirus capable of propagating and spreading through human gliomas |
| abstract |
Described are (a) parvovirus variants capable of propagating and spreading through human tumor cells which is obtainable by serially passaging a rodent parvovirus as starting strain in semi-permissive human tumor cells, and (b) parvovirus variants capable of propagating and spreading through human tumor cells characterized by particular amino acid deletions and/or substitutions, e.g. a deletion of several amino acids in the C-terminus of NS1/middle exon of NS2. A pharmaceutical composition containing such parvoviruses as well as their use for the treatment of cancer, preferably a glioblastoma, is also described. |
| priorityDate |
2010-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |