http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2011235538-B2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24356fead12f62379eb2dabac1e27e59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e35f7e567c072530870ed7001964e57c |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4354 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6888 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 |
filingDate | 2011-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d53df4a49f8af22ffe846dfbedd041f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a72ccd9f8faff726ddb5aed4ff4cc474 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_880e933f4a93a59bfbbb02afe2ec45e6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14aa1f66c53ca5095b1e293a410033b5 |
publicationDate | 2014-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | AU-2011235538-B2 |
titleOfInvention | Macrocyclic lactone resistance marker for Dirofilaria immitis |
abstract | The invention relates to a method for determining the responsiveness of a Dirofilaria spp. nematode to a macrocyclic lactone, by determining the genotype of the nematode at a position in a P-glycoprotein gene of the nematode corresponding to position 1 1, and optionally to position 618, in SEQ ID NO: 1, wherein the genotype GG at a position corresponding to position 1 1, or at positions corresponding to positions 1 1 and 618, in SEQ ID NO: 1 indicates that the nematode is likely resistant to the macrocyclic lactone. The invention also relates to methods for selecting a treatment to treat an animal infected with macrocyclic lactone resistant Dirofilaria spp nematode, and treating the animal; or for selecting a prophylactic to prevent an animal from becoming infected with a macrocyclic lactone resistant Dirofilaria spp nematode, and providing the prophylactic to the animal. The invention further relates to an isolated nucleic acid having at least 80% sequence identity to SEQ ID NO: 1. |
priorityDate | 2010-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 156.