http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2011205019-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37803d53d66a7b26da2ed06989eede12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 |
| filingDate | 2011-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99918ca55ef628955473952ad5b68276 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03ac42a992386a2769ce88379b48c514 |
| publicationDate | 2011-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AU-2011205019-A1 |
| titleOfInvention | Methods and compositions for the inhibition of modulation of T cell costimulatory pathway by a pathogenic agent |
| abstract | Docuinent2-2M7/20il The invention relates to methods and compositions for the inhibition of modulation 5 of T cell costimulatory pathway by a pathogenic agent. More particularly, the invention relates to the inhibition of activation of a T cell costimulatory pathway, preferably the CD28/B7 pathway, by a pyrogenic exotoxin, based on the inhibition of the direct interaction of a superantigen with a specific site within the dimer interface of a CD28 family member, using immunomodulatory peptides. The invention further provides 10 specific antagonist immunomodulatory peptides comprising an amino acid sequence which specifically binds to an amino acid sequence within the dimer interface of a T cell costimulatory pathway member. Compositions comprising said peptides and methods for the treatment of immune-related disorders are also provided by the invention. |
| priorityDate | 2003-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 315.