http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2011203202-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_059babf90e455b4228aeb41f2eed9887 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 |
| filingDate | 2011-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afa0eb06c7c06b2795dea5fcaa75575a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90e53ec0cb9a184945fcaf99b47212f1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f113398d976833dc3c1ae71430ca73a4 |
| publicationDate | 2014-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AU-2011203202-B2 |
| titleOfInvention | Methods of using sustained release aminopyridine compositions |
| abstract | A pharmaceutical composition which comprises a therapeutically effective amount of a aminopyridine dispersed in a release matrix, including, for example, a composition that can be formulated into a stable, sustained-release oral dosage formulation, such as a tablet which provides, upon administration to a patient, a therapeutically effective plasma level of the aminopyridine for a period of at about 12 hours and the use of the composition to treat various neurological diseases, including multiple sclerosis. A method of selecting individuals based on responsiveness to a treatment, including, for example, identifying individuals who responded to treatment with a sustained release fampridine composition. WO 20051099701 PCT/US2005/012427 35 Treatment means over time ** e 25 ------ CD O --- Racebo (N=47) 0 + Farrpridine Responders (N=58) Fi.1 titration 1 st stable 2nd stable 3rd stable *:Significantly better than placebo and fampridine non-responders &P < 0.001 for each). 5Significantly better than farnpridine non-responders Fig. 10 |
| priorityDate | 2004-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.