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filingDate 2010-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8aeec88c09d48011b0e72d8cb824842
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b66a196d0ec786aa686e981e6e2a3d2
publicationDate 2017-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber AU-2010366696-B9
titleOfInvention Improved glycan arrays and methods for their fabrication
abstract The invention relates to glycan arrays with quantified levels of glycan expression and a method for fabricating thereof. The method comprises quantitatively reacting an ω-aminoalkylglycan with an activated polymer of an acrylic acid derivative to obtain glycoconjugated polymer or copolymer and covalently attaching the (co)polymer to a functionalized substrate. The glycan arrays according to the invention comprise an co-aminoalkylglycan covalently attached to a functionalized substrate via a fluorescently labeled (co)polymer of an acrylic acid derivative. The copolymer of an acrylic acid derivative may comprise fluorescein cadaverine as a fluorescent label or lysine or aminated PEG. The functionalized substrate is selected from an epoxylated and aminated glass or plastic. The invention also provides a fluorescently labeled co-aminoalkylglycan conjugated polymer of an acrylic acid derivative for use in the fabrication of glycan arrays.
priorityDate 2010-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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