| abstract |
Provided are compounds, pharmaceutical compositions and methods of treatment or prophylaxis of certain neurologic disorders, including disorders related to NMDA receptor activation, including neuropsychiatric disorders, neurodegenerative diorders and other neurologic diseases, disorders and conditions including stroke, brain injury, epilepsy, neuropsychiatric disorders, mood disorders, chronic pain and related conditions. The compounds are of the general Formula I [structure], or a pharmaceutically acceptable salt, ester, prodrug or derivative thereof are provided: wherein Ar1, Ar2; m, n, p and q; A; R3; Q; Y; R; X; and Z are defined herein. |