http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2010331867-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3b87b47407d929b7852321461253c5fa |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 |
| filingDate | 2010-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f80467692dbf4472fb72c63335590d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_426de2ec2346e5b2a723de510f5f23d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd749dc64c0ab1ab5d3ca7676f772ba5 |
| publicationDate | 2012-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AU-2010331867-A1 |
| titleOfInvention | Composition comprising an amorphous non- crystalline glass form of azithromycin |
| abstract | The invention relates to an amorphous non-crystalline glass form (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R) -2-ethyl-3,4, 10- trihydroxy- 3,5,6,8,10,12,14- heptamethyl-15-oxo- 11- {[3,4,6- trideoxy-3- (dimethylamino) -β-D-xylo- hexopyranosyl]oxy}-1-oxa- 6- azacyclopentadec-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo- hexopyranoside or azithromycin having an infra-red pattern displaying characteristic relatively broad peaks at approximately 3500 and 1727 cm and characteristic peaks at approximately 2970 and 2938 cm. The invention further relates to a preparation method of increasing the solubility of azithromycin including the steps of selecting anhydrous, monohydrated or dihydrated azithromycin; elevating the temperature of the azithromycin to above the melting point thereof; and reducing the temperature of the melt sufficiently to allow it to set into an amorphous non-crystalline glass form (Form-ll) of azithromycin having relatively increased solubility without decreasing the structural stability thereof. |
| priorityDate | 2009-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.