http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2010267917-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_116c851e729089df9a427027272fa290 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D273-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D245-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D273-08 |
| filingDate | 2010-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_510ff9d547d2ba6795fe7ebf5ac81f05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_710b39e8f281c6824e7809bcdeabb620 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f79bbf39e0d0806f8b92016d04bf5151 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5b3c77c823a69265b3c2af6fccfa1d0 |
| publicationDate | 2012-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AU-2010267917-A1 |
| titleOfInvention | Novel conjugates, preparation thereof, and therapeutic use thereof |
| abstract | The invention relates to a targeting agent, to which at least one cryptophycin is attached, of the formula (I), where: R is a halogen atom and R is an OH group, an acyl group derived from an amino acid AA or a (C-C)alkanoyloxy group; or else R and R together form an epoxy unit; AA denotes a natural or artificial amino acid; R3 is a (C-C)alkyl group; R4 and R5 are both H or together form a CH=CH double bond between C13 and C14; R and R are, independently from one another, H or a (C-C)alkyl group; R and R are, independently from one another, H or a (C-C)alkyl group; R is at least one substituent of the phenyl core selected from among: H, an OH group, (C-C)alkoxy, a halogen atom or a NH, NH(C-C)alkyl, or N(C-C)alkylgroup; R is at least one substituent of the phenyl core selected from among H or a (C- C)alkyl group; the targeting agent and the cryptophycin derivative being covalently bonded, the bond being located at the ortho (o), meta (m), or para (p) position of the phenyl core containing the CR unit. |
| priorityDate | 2009-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 325.