| abstract |
The invention relates to a compound of formula (Ia), wherein n is an integer between 2 and 10, R and R independently represent a substituent selected from the group consisting of hydrogen, C-Calkyl, C-C cycloalkyl and aminoalkyl, or R and R are taken together with the nitrogen atom to which they are attached to form a four to ten-membered heterocycle, R represents independently in each of the n units a substituent selected from the group consisting of hydrogen, C-C alkyl, halogen, alkoxy, aminoalkyl and alkylamino; or a pharmaceutically acceptable salt thereof, with the proviso that the 5-fluorotryptamine is excluded, for the treatment or the prophylaxis of neuroinflammatory diseases or disorders. The invention also relates to a pharmaceutical composition, a method for inhibiting myeloperoxidase enzyme activity, to a method for inhibiting Low density lipoproteins oxidation. |