http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2010206224-B2

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filingDate 2010-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2012-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2012-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber AU-2010206224-B2
titleOfInvention Pharmaceutical compositions comprising a HCV polymerase inhibitor prodrug
abstract The present invention provides novel formulations of isobutyric acid (2R,3R,4R,5R)-5-(4-amino-2-oxo-2H-pyrimidin-1-yl)-4-fluoro-2-isobutyryloxymethyl-4-methyl-tetrahydro-furan-3-yl ester) and hydroxypropylcellulose that provide high bulk density, low particle size better suited for improved compression and flow, good compression, and fast dissolution profiles.
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