abstract |
The invention relates to methods to treat specified clinical disorders such as hyperglycemia, type 2 diabetes, arthritis and multiple sclerosis. The invention also 5 provides methods to identify and characterize drugs, which are characterized in part by eliciting a variable biologic or therapeutic effect on a biomolecule at one time and relative normalization of the biomolecule at another time point. Compounds include 17ax-ethynylandrost-5-ene-3p,7p,17p-triol or androst-5-ene-3p,4p,16at,17p-tetrol, which can be used as reference standards to facilitate assessing and characterizing 10 such candidate drugs. 2223070.1 (GHMatters) |