| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb596f03d029321340c965e75de6564a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-31 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6811
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6889
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6803
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-59 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 |
| filingDate |
2009-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_998f6c50c3ab6954c7903cc6bf325e0e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c5a456c006de073f309bc9c92cf134b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a90e136922f545605545c42ae6519a0c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87f194a68a2db1aa4977e821a3a83518
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e7d1be5cdbc9102f57b9982ab2dfefd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41e857678586c17080a72976de8cd1f2 |
| publicationDate |
2012-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
AU-2009274738-B2 |
| titleOfInvention |
A polypeptide complex comprising non-peptidyl polymer having three functional ends |
| abstract |
Disclosed is a protein complex, comprising a physiologically active polypeptide, a dimeric protein and a non-peptidyl polymer having three functional ends(3-arm), with the linkage of both the physiologically active polypeptide and the dimeric protein to the 3-arm non-peptidyl polymer via respective covalent bonds. The protein complex guarantees the long acting activity and biostability of a physiologically active polypeptide. Having the ability to maintain the bioactivity of physiologically active polypeptides or peptides highly and to significantly improve the serum half life of the polypeptides or peptides, the protein complex can be applied to the development of sustained release formulations of various physiologically active polypeptide drugs. Also, it utilizes raw materials including the physiologically active polypeptides without significant loss, thereby increasing the production yield. Further, it can be easily purified. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10071171-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11040110-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9636420-B2 |
| priorityDate |
2008-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |