| abstract |
[PROBLEMS] To provide a compound useful as an NMDA receptor antagonist. [MEANS FOR SOLVING PROBLEMS] A study was made on a compound having an antagonistic activity on an NMDA receptor, and it was confirmed that a fused indane compound according to the invention had an excellent antagonistic activity on an NMDA receptor.The fused indane compound has an excellent antagonistic activity on an NMDA receptor, and therefore can be used as an active ingredient for a prophylactic and/or therapeutic agent for Alzheimer's disease, vascular dementia, Parkinson's disease, intractable depression, attention deficit hyperactivity disorder, migraine or the like. |