http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2008272918-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_785ac2b35073f5a6d251678e6fb31b6f |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-04 |
filingDate | 2008-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2012-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7842477ed54bc2047e8763331de6c21e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_355a10a8b18a058020bb88dd04f50c89 |
publicationDate | 2012-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | AU-2008272918-B2 |
titleOfInvention | 6-disubstituted bicyclic nucleic acid analogs |
abstract | The present disclosure describes 6-disubstituted bicyclic nucleosides, oligomeric compounds prepared therefrom and methods of using the oligomeric compounds. More particularly, the 6-disubstituted bicyclic nucleosides each comprise a 2'-O-C(Ri)(R2)-4' or 2'-O- C=(R3)(R.4)-4' bridge wherein each R is, independently a substituent group and Ri and R2 include H. The 6-disubstituted bicyclic nucleosides are useful for enhancing properties of oligomeric compounds including nuclease resistance. In certain embodiments, the oligomeric compounds provided herein hybridize to a portion of a target RNA resulting in loss of normal function of the target RNA. |
priorityDate | 2007-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 986.