http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2008254037-B2

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filingDate 2008-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f6d43f9b186b538ac4446f1058cf930
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publicationDate 2013-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber AU-2008254037-B2
titleOfInvention Crystalline micropowder particles
abstract Crystalline particles of N-(17-cyclopropylmethyl-4,5α-epoxy-3,14-dihydroxy-morphinan-6β-yl)-phthalimide or a pharmaceutically acceptable salt thereof. Theses crystalline particles have a particle diameter distribution, wherein the particle diameter (D50) at the point attaining a cumulative frequency of 50% in volume distribution counted from the smallest particle diameter ranges from 1 to 30 μm while the particle diameter (D90) at the point attaining a cumulative frequency of 90% in volume distribution counted from the smallest particle diameter is not more than 90 μm, and a degree of crystallization of 80% or more. These crystalline particles make it possible to improve the biological availability of the active ingredient while ensuring the storage stability of the above-described compound.
priorityDate 2007-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 31.