Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_20967971c592afd045725838e52fd32e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-24222 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-24243 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-186 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-707 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5767 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
filingDate |
2008-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2013-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00450577151b8e67a693cd889249ba86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb18d024c27cea2d92b63b378376fc41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f16e353bcd6a6c131e1faab5392e8cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5dbd5e94791905e50b301383507dc3ab |
publicationDate |
2013-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
AU-2008246622-B2 |
titleOfInvention |
HCV gene |
abstract |
It is intended to provide a hepatitis C virus gene, a replicon RNA originating in this gene, a replicon-replicating cell having this replicon RNA transferred thereinto and a method of screening a drug by using this replicon-replicating cell. A replicon-replicating cell can be constructed by transferring into a cell a replicon RNA containing: (A) a polynucleotide which comprises the base sequence represented by SEQ ID NO:5; (B) a polynucleotide which comprises the base sequence represented by SEQ ID NO:7; (C) a polynucleotide encoding a polypeptide comprising the amino acid sequence represented by SEQ ID NO:6; (D) a polynucleotide encoding a polypeptide comprising the amino acid sequence represented by SEQ ID NO:8; or (E) a polynucleotide comprising a base sequence having a 90% or more homology with the base sequence represented by SEQ ID NO:5 or 7: or a replicon RNA of genotype 1b which contains a nucleotide encoding leucine at the 1804-position and lysine at the 1996-position in the amino acid sequence of hepatitis C virus polyprotein and a polynucleotide encoding NS4B protein. Use of this replicon-replicating cell makes it possible to screen a drug. |
priorityDate |
2007-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |