| abstract |
The invention relates to the use of a compound of the formula (I), or a pharmaceutically acceptable salt thereof, for the manufacture of a medicament for use in modulating an immune or inflammatory response: wherein: Z = O or S; n = 1 - 3; R = -COR, -C(O)SR, -C(O)NHR,-C(S)OR, -C(S)SR, -C(S)NHR, -C(NH)SR or -C(NH)NHR, wherein R is -H or alkyl; R = -H, -CHR or -CHCHR, wherein R independently has one of the meanings of R; B = -NR-, -CHNR-, -CHCHNR-, -CHCHR- or -CHO-, wherein R is H or a C alkyl, alkenyl or alkynyl group, and R is H or a C alkyl or alkoxy group; A = wherein R = -NH or -OH, C and D are each, independently, a 5- or 6-membered, substituted or unsubstituted, aromatic or non-aromatic ring which may also contain one or more heteroatoms, and C is connected to group B in any available position. |