http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2007306556-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7450f8b709a8f9c94070d7468a736d31 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-582 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1272 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 |
filingDate | 2007-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eee2f6bdcd8b97980a6cc23e9e20300d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b17ea10cd755452fbcdbe4b8697a9b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57ac981592dab8bb4600b283eb79bde5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0a3e01190a1d4cf9d6ca3ab32c1d960 |
publicationDate | 2014-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | AU-2007306556-B2 |
titleOfInvention | Improvements in or relating to amphoteric liposomes |
abstract | An amphoteric liposome composed of a mixture of lipids, said mixture comprising a cationic amphiphile, an anionic amphiphile and optionally one or more neutral amphiphiles, at least one of said cationic and anionic amphiphiles being chargeable and the respective amounts of said cationic and anionic amphiphiles being selected such there is a stoichiometric excess of positively charged cationic amphiphile at a first lower pH, a stoichiometric excess of negatively charged anionic amphiphile at a second higher pH and said mixture has an isoelectric point intermediate said first and second pHs; characterised in that said positively charged cationic and negatively charged anionic amphiphiles are adapted to form a lipid salt with one another at said isoelectric point. Also disclosed are methods of predicting the fusogenicity of an amphoteric liposome at a given pH, formulating an amphoteric liposome and loading an amphoteric liposome with a cargo moiety. |
priorityDate | 2006-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 314.