http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2007202256-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a43ef275ae6f6fafc66975041eb60aa7 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-24 |
| filingDate | 2007-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_482714cfa175e5ecacb76a7f75ebf52b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7fb7630ea0ab6970968688365534a0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2ab10b5ae968eaa40cb496d59f6dbb3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e64664b34e94348269a92f9b502f3bad |
| publicationDate | 2011-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AU-2007202256-B2 |
| titleOfInvention | High mannose proteins and methods of making high mannose proteins |
| abstract | P:\OPER\HPM\Trankaryonc Thap-es0222487\i Clams doc.- I)5/2(7 The invention features a method of producing a high mannose glucocerebrosidase (hmGCB) which includes: providing a cell which is capable of expressing glucocerebrosidase (GCB), and allowing production of GCB having a precursor oligosaccharide under conditions which prevent the removal of at least one mannose residue distal to the pentasaccharide core of the precursor oligosaccharide of GCB, to thereby produce an hmGCB preparation. Preferably, the condition which prevents the removal of at least one mannose residue distal to the pentasaccharide core is inhibition of a class 1 processing manosidase and/or a class 2 processing manosidase. The invention also features an hmGCB preparation and methods of using an hmGCB preparation. |
| priorityDate | 2000-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 276.