http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2006328424-B2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_382ccfc2ebebcaee15aa7cda4cee86bc |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61J2200-20 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61J3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61J3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-148 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J2-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61J3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 |
filingDate | 2006-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_570e9f8e49305b94bfc5c325a6f355e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de96f956be3f4fc2d97c488bd45af70f |
publicationDate | 2013-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | AU-2006328424-B2 |
titleOfInvention | Method of producing drug-containing wax matrix particles, extruder to be used in the method and sustained-release preparation containing cilostazol |
abstract | It is intended to provide a method of conveniently producing drug-containing wax matrix particles (in particular, drug-containing wax matrix particles having an average particle diameter of 1 mm or less) through melting and spraying steps without suffering from a jamming failure caused by the recrystallization of the once molten drug. Namely, drug-containing wax matrix particles containing a drug and a wax are produced via the following steps (i) and (ii): (i) the step of feeding the drug and wax as described above into an extruder wherein the temperatures of a barrel (1) and a die have been controlled to a level higher than the melting point of the wax; and (ii) the step of melt-kneading the drug with the wax in the extruder as described above and simultaneously spraying out the melt-kneaded mixture comprising the drug and the wax from a spray nozzle (5), which is attached directly to a die (3) provided at the tip of the barrel (1) in the extruder, into an atmosphere at a temperature lower than the melting point of the wax to thereby form particles. |
priorityDate | 2005-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 894.