| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_443ab643bec9257fc738751c2850ac22 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-33 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6829
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-21 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-195
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
| filingDate |
2006-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbb403a70fe25ab69ce23bffc615d119
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1797719b0837f8a2e330f751d404bab2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbd1ebdb61979407fb7e274eda482082
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c309319d842d1de7a50b7d6b9a02933
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4075628eba99b22fc9880fa21d9c8658
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3048ae0ab9eb11177a9055ceca798b4f |
| publicationDate |
2012-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
AU-2006275865-B2 |
| titleOfInvention |
Mutated Pseudomonas exotoxins with reduced antigenicity |
| abstract |
The invention provides mutated Pseudomonas exotoxins (PE) that have reduced immunogenicity compared to PEs containing the native sequence. The PEs of the invention have one or more individual mutations of positions of the native sequence of PE that reduce antibody binding to one or more PE epitopes. Nucleic acids encoding the mutated PEs, chimeric molecules comprising them, compositions comprising the chimeric molecules and methods of using them, are also provided. |
| priorityDate |
2005-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |